Kansas City Chiefs vs Buffalo Bills 10/16/22 NFL Picks, Predictions, Odds

Buffalo Bills (4-1) vs. Kansas City Chiefs (4-1)
16 October 2022 at 4:25 PM EDT
The Line: Kansas City Chiefs +2.5 / Buffalo Bills -2.5; Over/Under: +53.5
(Click here for latest odds)

The Kansas City Chiefs and Buffalo Bills kick off a Week 6 NFL matchup from Arrowhead Stadium on Sunday.

The Buffalo Bills will look to build on back-to-back wins after a 38-3 victory over the Steelers to improve to 4-1 on the year as a result. Josh Allen has thrown for 1,651 yards, 14 touchdowns and 4 interceptions on 66.8% passing while also leading the Bills on the ground with 225 rushing yards this season. Stefon Diggs leads Buffalo’s receiving group with 39 catches for 508 yards and 5 TDs, while Gabriel Davis also has 309 receiving yards and 3 TDs this season. Three other Bills also have 100+ receiving yards on the year. On defense, Matt Milano has a team-high 29 total tackles, while Von Miller and Greg Rousseau each have a team-high 4 sacks this season.

The Kansas City Chiefs will look to build on their own back-to-back wins after also climbing to 4-1 with a narrow 30-29 victory over Las Vegas on Monday night last time out. Patrick Mahomes has thrown for 1,398 yards, 15 touchdowns and 2 interceptions on 66.7% passing, while Clyde Edwards-Helaire has a team-high 223 rushing yards and a pair of touchdowns. Travis Kelce leads KC’s receiving corps with 33 catches for 347 receiving yards and 7 TDs, while JuJu Smith-Schuster also has 257 receiving yards. Marquez Valdes-Scantling also has 258 receiving yards and Mecole Hardman and the aforementioned Edwards-Helaire each also have 100+ receiving yards this season. On defense, Nick Bolton has a team-high 37 total tackles with a pair of sacks, while L’Jarius Snead has a team-high 3 sacks this season as well.

Buffalo is 7-2-2 ATS in their last 11 games overall and 2-5-1 ATS in their last 8 games against a team with a winning record while the under is 6-2 in their last games dating back to October 8th. Kansas City is 6-2 ATS in their last 8 home games and 7-3 ATS in their last 10 games against a team with a winning record while the over is 10-3 in their last 13 games overall.

I’m getting the thing done across the board in this one, but I’m not sure where else to look other than that over. KC’s offense is alive again and should enjoy a battered Bills secondary, while Buffalo looked really good against the Steelers last week and has more than enough offensive firepower to match scoring with the Chiefs here. Get your popcorn. This one is going to be good. Give me over.

Chris Ruffolo’s Free Picks:

Above 53.5

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